Ipamorelin
Selective ghrelin-receptor pentapeptide.
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For research and laboratory use only. Not for human or veterinary consumption.
About this compound
Ipamorelin is a selective, five-residue peptide that acts as a growth-hormone secretagogue by engaging the ghrelin receptor (GHS-R). Compact and highly targeted, it has become one of the most studied secretagogues in modern GH-axis research.
What sets ipamorelin apart is its reported selectivity. Unlike many older secretagogues, research models point to minimal involvement of cortisol and prolactin pathways, giving it a notably clean signaling profile. This focused action is precisely why it is so prized in laboratory work.
Ipamorelin is frequently paired with a GHRH analog such as CJC-1295 (no-DAC) to study complementary signaling routes. Supplied as a stable lyophilized powder for laboratory and research use only.
Research overview
Selective ghrelin-receptor activation
Ipamorelin binds the ghrelin receptor (GHS-R) to stimulate growth-hormone release from the pituitary. Its small, highly specific structure gives it a precise mechanism that investigators value for predictable, well-defined signaling. This targeted action is the foundation of its popularity in secretagogue research.
Clean signaling profile
A defining feature of ipamorelin is its reported low involvement of cortisol and prolactin compared with earlier secretagogues. Research models suggest it can support GH release without the broader hormonal noise associated with less selective compounds. This clean profile makes it a preferred reference peptide in GH-axis studies.
GH & IGF-1 axis research
By promoting pulsatile growth-hormone secretion, ipamorelin is widely used to study downstream effects across the GH-IGF-1 axis. Investigators rely on it to probe how secretagogue-driven GH release relates to metabolic and regenerative endpoints in research models. Its consistency makes it a dependable experimental tool.
Synergy with GHRH analogs
Ipamorelin is most often paired with GHRH analogs such as CJC-1295 (no-DAC), combining ghrelin-pathway and GHRH-pathway signaling. This complementary approach is among the most explored combinations in growth-hormone secretagogue research. The two are studied together to better characterize how distinct upstream signals converge on GH output.
Research-grade quality
Ipamorelin is supplied as a stable lyophilized powder for laboratory and research use only. It is prepared to a high representative purity standard suited to rigorous experimental protocols. It is not intended for human or veterinary use.
Prep it right
Reconstitute gently — add bacteriostatic water down the vial wall and swirl, don't shake. The lyophilized powder goes fully into solution without foaming.
Reconstituting? Work out concentration and draw volume in the reconstitution calculator.
Store the lyophilized vial at −20 °C, protected from light. Once reconstituted, refrigerate and use it within the diluent's window.
Lyophilization (freeze-drying) removes water under low pressure so the peptide sublimates from solid to vapor, leaving a stable powder that preserves its integrity until it is reconstituted with bacteriostatic water. Lyophilized vials are robust in transit and reach their longest shelf life when stored cold and protected from light.
All products are sold for laboratory and research use only and are not for human or veterinary consumption, diagnosis, or treatment of any kind. These statements have not been evaluated by the U.S. Food and Drug Administration. The products and statements are not intended to diagnose, treat, cure, or prevent any disease. Amino Meta is a chemical supplier and is not a compounding pharmacy or an outsourcing facility as defined under sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act.
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