
CJC-1295 (no DAC)
GHRH analog (Mod GRF 1-29).
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For research and laboratory use only. Not for human or veterinary consumption.
About this compound
CJC-1295 (no-DAC), also known as Mod GRF 1-29, is a stabilized analog of growth-hormone-releasing hormone (GHRH). Without the Drug Affinity Complex of its long-acting counterpart, this form is engineered for a short, sharp signal that works with the body's own rhythms rather than overriding them.
By engaging the GHRH receptor, CJC-1295 (no-DAC) supports the natural, pulsatile release of growth hormone from the pituitary. This pulse-preserving design has made it a favored tool in GH-axis research, where investigators want to amplify endogenous signaling while keeping its native pattern intact.
It is most often studied alongside a ghrelin-receptor secretagogue such as ipamorelin — a pairing prized for its complementary mechanisms and clean signaling profile. Supplied as a stable lyophilized powder for laboratory and research use only.
Research overview
Pulsatile GH-axis support
CJC-1295 (no-DAC) is studied for its ability to engage the GHRH receptor and reinforce the pituitary's own pulsatile release of growth hormone. Because the no-DAC form clears quickly, research models use it to enhance signaling while preserving the natural peaks and troughs of GH secretion. This rhythm-respecting approach is a key reason the peptide is so widely explored in GH-axis work.
Stabilized GHRH analog
Built on the active 1-29 fragment of GHRH and stabilized against rapid enzymatic breakdown, CJC-1295 (no-DAC) delivers a more reliable signal than the unmodified native sequence. Targeted amino-acid substitutions improve resistance to degradation while keeping the molecule's interaction with the GHRH receptor faithful. The result is a clean, well-characterized research peptide.
Synergy with ipamorelin
In research settings, CJC-1295 (no-DAC) is frequently paired with ipamorelin, a selective ghrelin-receptor secretagogue. The two act through distinct but complementary pathways, and investigators often study them together to explore how GHRH-driven and ghrelin-driven signals combine. This combination is among the most popular in growth-hormone secretagogue research.
Body composition & recovery research
Through its support of the GH axis, CJC-1295 (no-DAC) is a frequent subject in studies examining lean-mass dynamics, fat metabolism, and tissue recovery in research models. Its pulse-preserving profile makes it a useful comparator when investigating how amplified yet natural GH signaling relates to body-composition outcomes. These applications keep it central to metabolic and regenerative research.
Research-grade quality
Each lot is supplied as a stable lyophilized powder intended strictly for laboratory and research use. The peptide is prepared to a high representative purity standard suitable for demanding experimental work. It is not for human or veterinary use.
Prep it right
Reconstitute gently — add bacteriostatic water down the vial wall and swirl, don't shake. The lyophilized powder goes fully into solution without foaming.
Reconstituting? Work out concentration and draw volume in the reconstitution calculator.
Store the lyophilized vial at −20 °C, protected from light. Once reconstituted, refrigerate and use it within the diluent's window.
Lyophilization (freeze-drying) removes water under low pressure so the peptide sublimates from solid to vapor, leaving a stable powder that preserves its integrity until it is reconstituted with bacteriostatic water. Lyophilized vials are robust in transit and reach their longest shelf life when stored cold and protected from light.
All products are sold for laboratory and research use only and are not for human or veterinary consumption, diagnosis, or treatment of any kind. These statements have not been evaluated by the U.S. Food and Drug Administration. The products and statements are not intended to diagnose, treat, cure, or prevent any disease. Amino Meta is a chemical supplier and is not a compounding pharmacy or an outsourcing facility as defined under sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act.
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