Epitalon
Pineal-modeled telomerase tetrapeptide.
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For research and laboratory use only. Not for human or veterinary consumption.
About this compound
Epitalon is a synthetic four-amino-acid peptide (Ala-Glu-Asp-Gly) modeled on epithalamin, a natural complex secreted by the pineal gland. First developed and studied at the St. Petersburg Institute of Bioregulation and Gerontology, it is one of the most extensively explored bioregulator peptides in longevity and cellular-aging research.
Epitalon is prized in research circles for its connection to telomere biology, circadian regulation, and the body's internal clock. Its compact sequence interacts with pathways that govern cellular timekeeping and renewal, making it a cornerstone compound for investigators studying graceful cellular aging.
Supplied as a stable lyophilized powder for laboratory reconstitution, this listing is intended strictly for research use only (RUO) and is not for human or animal consumption.
Research overview
Telomere & telomerase research
Epitalon is best known for its role in telomerase research, where it is studied for its potential to support the enzyme responsible for maintaining telomere length. Because telomere shortening is a hallmark of cellular aging, this mechanism makes Epitalon a focal point for investigators exploring cellular longevity. Research models continue to examine how the peptide influences telomere dynamics and the replicative capacity of cells.
Cellular senescence & longevity
As a pineal-derived bioregulator, Epitalon is widely studied for its relationship to cellular senescence — the gradual decline in cellular function that accompanies aging. Research suggests it may help support healthier cellular cycling and resilience in aged-tissue models. This positions Epitalon as a flagship compound in the broader study of biological aging and cellular renewal.
Melatonin & circadian rhythm
Given its origin in the pineal complex, Epitalon is closely tied to melatonin and circadian-rhythm research. Studies explore how it may help normalize the secretion patterns that govern the sleep-wake cycle and the body's internal clock. This makes it an important tool for investigators examining rhythm regulation and pineal signaling in research settings.
Pineal bioregulation
Modeled directly on the natural epithalamin complex, Epitalon represents a focused approach to pineal bioregulation research. It is studied for its potential to support the gland's signaling role across multiple physiological systems. Decades of work at the St. Petersburg Institute of Bioregulation and Gerontology have established it as a benchmark peptide in this field.
Cellular resilience & renewal
Beyond its telomere connection, Epitalon is investigated for broader effects on cellular resilience and renewal in research models. Its role in supporting orderly cellular function makes it attractive to researchers studying healthy aging at the tissue level. As one of the most studied short bioregulator peptides, it continues to anchor longevity-focused investigation.
Prep it right
Reconstitute gently — add bacteriostatic water down the vial wall and swirl, don't shake. The lyophilized powder goes fully into solution without foaming.
Reconstituting? Work out concentration and draw volume in the reconstitution calculator.
Store the lyophilized vial at −20 °C, protected from light. Once reconstituted, refrigerate and use it within the diluent's window.
Lyophilization (freeze-drying) removes water under low pressure so the peptide sublimates from solid to vapor, leaving a stable powder that preserves its integrity until it is reconstituted with bacteriostatic water. Lyophilized vials are robust in transit and reach their longest shelf life when stored cold and protected from light.
All products are sold for laboratory and research use only and are not for human or veterinary consumption, diagnosis, or treatment of any kind. These statements have not been evaluated by the U.S. Food and Drug Administration. The products and statements are not intended to diagnose, treat, cure, or prevent any disease. Amino Meta is a chemical supplier and is not a compounding pharmacy or an outsourcing facility as defined under sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act.
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