Survodutide
GLP-1 / glucagon dual agonist.
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For research and laboratory use only. Not for human or veterinary consumption.
About this compound
Survodutide is a single-molecule GLP-1 and glucagon dual agonist engineered for a balanced, two-pathway metabolic signal. Built on a glucagon backbone with GLP-1 / exendin-derived substitutions and a fatty-diacid tail for extended stability, it unites appetite-and-glucose control with energy-expenditure activity in one purpose-built peptide.
Its glucagon-rooted design gives it particular research relevance to energy metabolism and hepatic function, while the GLP-1 substitutions add incretin-driven appetite and glucose benefits. The fatty-diacid tail supports a long-acting profile and steady signaling across the research window.
Supplied as a stable lyophilized powder, Survodutide is a leading single-molecule dual-agonist reference compound for energy-metabolism and hepatic research. For laboratory and research use only.
Research overview
Single-molecule GLP-1 & glucagon agonism
Survodutide combines GLP-1 and glucagon activity within one engineered molecule, built on a glucagon backbone with GLP-1 / exendin substitutions. This unified design delivers a coordinated dual-pathway signal. In research models, its single-molecule construction makes it a clean and reproducible tool for studying dual-agonist biology.
Energy metabolism
The glucagon foundation of Survodutide places energy metabolism and expenditure at the center of its research profile. Glucagon signaling is studied for its role in driving metabolic rate and mobilizing stored energy. This makes Survodutide a focal compound for energy-balance investigation.
Hepatic research
Survodutide draws significant research interest for its effects on hepatic function and liver-related metabolism, where glucagon signaling is highly active. By influencing hepatic energy and lipid handling, it is studied as a tool for liver-metabolism research. This hepatic focus is a defining feature of its research appeal.
Appetite & glucose control
The GLP-1 / exendin substitutions give Survodutide incretin-driven appetite and glucose-handling activity. This complements its glucagon-linked energy expenditure for a balanced metabolic effect. Together the pathways support comprehensive metabolic regulation in research settings.
Long-acting stability
Survodutide's fatty-diacid tail extends its half-life, supporting sustained receptor engagement across the research window. This long-acting design avoids the rapid clearance of shorter peptides and delivers steady, reproducible signaling. Its stability profile makes it well suited to longitudinal metabolic and hepatic study designs.
Prep it right
Reconstitute gently — add bacteriostatic water down the vial wall and swirl, don't shake. The lyophilized powder goes fully into solution without foaming.
Reconstituting? Work out concentration and draw volume in the reconstitution calculator.
Store the lyophilized vial at −20 °C, protected from light. Once reconstituted, refrigerate and use it within the diluent's window.
Lyophilization (freeze-drying) removes water under low pressure so the peptide sublimates from solid to vapor, leaving a stable powder that preserves its integrity until it is reconstituted with bacteriostatic water. Lyophilized vials are robust in transit and reach their longest shelf life when stored cold and protected from light.
All products are sold for laboratory and research use only and are not for human or veterinary consumption, diagnosis, or treatment of any kind. These statements have not been evaluated by the U.S. Food and Drug Administration. The products and statements are not intended to diagnose, treat, cure, or prevent any disease. Amino Meta is a chemical supplier and is not a compounding pharmacy or an outsourcing facility as defined under sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act.
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