Mazdutide
GLP-1 / glucagon dual agonist (oxyntomodulin analog).
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For research and laboratory use only. Not for human or veterinary consumption.
About this compound
Mazdutide is a lipidated oxyntomodulin analog that functions as a balanced GLP-1 and glucagon dual agonist. By engaging both the appetite-and-glucose incretin pathway and the energy-expenditure-linked glucagon pathway, it brings a two-sided metabolic signal to research — pairing intake control with active energy metabolism.
Its oxyntomodulin-inspired design and lipidation give it sustained activity and a balanced receptor profile, with particular research interest in energy expenditure and hepatic lipid handling. This dual reach makes it a compelling subject for both weight-management and liver-metabolism investigation.
Supplied as a stable lyophilized powder, Mazdutide is a leading oxyntomodulin-analog reference compound for dual-agonist metabolic research. For laboratory and research use only.
Research overview
Balanced GLP-1 & glucagon agonism
Mazdutide engages both the GLP-1 and glucagon receptors in a deliberately balanced ratio, modeled on the natural hormone oxyntomodulin. This dual action pairs appetite and glucose control with energy-expenditure signaling. In research models, its balanced profile is prized for capturing both sides of metabolic regulation.
Energy expenditure
The glucagon component of Mazdutide brings active energy expenditure into focus, distinguishing it from appetite-suppression-only agonists. Glucagon signaling is studied for its role in raising metabolic rate and mobilizing stored energy. This makes Mazdutide a valued tool for energy-metabolism research.
Hepatic lipid handling
Mazdutide draws strong research interest for its influence on hepatic lipid metabolism, an area where glucagon signaling is especially active. By supporting healthier fat handling in the liver, it is studied for its effects on hepatic energy and lipid balance. This positions it as relevant to liver-metabolism investigation.
Appetite & glucose control
Through its GLP-1 activity, Mazdutide supports appetite regulation and steadier glucose handling in research settings. This incretin-driven control complements its glucagon-linked energy expenditure. The pairing creates a comprehensive metabolic signal valued for body-composition research.
Body composition
By combining appetite control with enhanced energy expenditure, Mazdutide supports favorable body-composition shifts in research models. Its dual mechanism works on both the intake and output sides of energy balance. This breadth makes it a notable subject for weight-management research.
Prep it right
Reconstitute gently — add bacteriostatic water down the vial wall and swirl, don't shake. The lyophilized powder goes fully into solution without foaming.
Reconstituting? Work out concentration and draw volume in the reconstitution calculator.
Store the lyophilized vial at −20 °C, protected from light. Once reconstituted, refrigerate and use it within the diluent's window.
Lyophilization (freeze-drying) removes water under low pressure so the peptide sublimates from solid to vapor, leaving a stable powder that preserves its integrity until it is reconstituted with bacteriostatic water. Lyophilized vials are robust in transit and reach their longest shelf life when stored cold and protected from light.
All products are sold for laboratory and research use only and are not for human or veterinary consumption, diagnosis, or treatment of any kind. These statements have not been evaluated by the U.S. Food and Drug Administration. The products and statements are not intended to diagnose, treat, cure, or prevent any disease. Amino Meta is a chemical supplier and is not a compounding pharmacy or an outsourcing facility as defined under sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act.
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