Cagrilintide
Long-acting amylin analog.
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For research and laboratory use only. Not for human or veterinary consumption.
About this compound
Cagrilintide is a long-acting amylin analog built on a pramlintide backbone and engineered for extended, sustained activity. By engaging amylin and calcitonin-receptor signaling, it taps into a satiety pathway that runs parallel to — and complements — the GLP-1 incretin system, giving it a distinctive role in appetite and energy-balance research.
Its long-acting profile delivers smooth, durable signaling across the research window, and it is frequently studied in combination with GLP-1 agonists, where the two pathways are explored for their complementary effects on satiety and metabolic balance.
Supplied as a stable lyophilized powder, Cagrilintide is a leading amylin-analog reference compound for appetite, satiety, and combination-metabolic investigation. For laboratory and research use only.
Research overview
Amylin & calcitonin-receptor signaling
Cagrilintide engages the amylin and calcitonin-receptor family, a satiety system distinct from the incretin pathways. This gives it a unique mechanism for influencing appetite and energy balance. In research models, its targeted receptor activity makes it a clean tool for studying amylin biology.
Appetite & satiety regulation
By acting on amylin-driven satiety circuits, Cagrilintide promotes a sense of fullness and reduces drive to feed in research settings. This appetite-regulating action is the core of its metabolic-research appeal. Investigators value it for probing satiety signaling outside the GLP-1 system.
Energy balance
Cagrilintide's influence on satiety extends to broader energy-balance regulation, supporting steadier control of intake and utilization. This positions it as a useful tool for studying how amylin signaling shapes metabolic equilibrium. Its long-acting design supports consistent energy-balance research over time.
Complementary GLP-1 combination
Cagrilintide is frequently studied alongside GLP-1 agonists, where amylin and incretin signaling are explored as complementary satiety pathways. This combination interest is a major reason for its prominence in metabolic research. Together, the pathways are investigated for their potential additive effects on appetite and body composition.
Long-acting stability
Engineered on a pramlintide backbone for an extended half-life, Cagrilintide delivers durable, sustained signaling across the research window. This long-acting profile avoids the rapid clearance of earlier amylin analogs. Its stability makes it well suited to longitudinal satiety and energy-balance study designs.
Prep it right
Reconstitute gently — add bacteriostatic water down the vial wall and swirl, don't shake. The lyophilized powder goes fully into solution without foaming.
Reconstituting? Work out concentration and draw volume in the reconstitution calculator.
Store the lyophilized vial at −20 °C, protected from light. Once reconstituted, refrigerate and use it within the diluent's window.
Lyophilization (freeze-drying) removes water under low pressure so the peptide sublimates from solid to vapor, leaving a stable powder that preserves its integrity until it is reconstituted with bacteriostatic water. Lyophilized vials are robust in transit and reach their longest shelf life when stored cold and protected from light.
All products are sold for laboratory and research use only and are not for human or veterinary consumption, diagnosis, or treatment of any kind. These statements have not been evaluated by the U.S. Food and Drug Administration. The products and statements are not intended to diagnose, treat, cure, or prevent any disease. Amino Meta is a chemical supplier and is not a compounding pharmacy or an outsourcing facility as defined under sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act.
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